- “A gene variant tied to autism rewires the brain"
- "Now we can begin to unravel the mystery of how genes rearrange the brain's circuitry, not only in autism but in many related neurological disorders."
- “Regardless of their diagnosis, the children carrying the risk variant showed a disjointed brain. The frontal lobe was over-connected to itself and poorly connected to the rest of the brain”
- "If we determine that the CNTNAP2 variant is a consistent predictor of language difficulties, we could begin to design targeted therapies to help rebalance the brain and move it toward a path of more normal development."
M. Kos et al., CNTNAP2 and language processing in healthy individuals as measured with ERPs. PLOS One 7, (2012).
G. C. Tan, T. F. Doke, J. Ashburner, N. W. Wood, R. S. Frackowiak, Normal variation in fronto-occipital circuitry and cerebellar structure with an autism-associated polymorphism of CNTNAP2. Neuroimage 53, 1030 (2010).
H. C. Whalley et al., Genetic variation in CNTNAP2 alters brain function during linguistic processing in healthy individuals. Am. J. Med. Genet. B 156B, 941 (2011).